PHARMACOLOGICAL PROPERTIES Benzoyl Peroxide Gel:

for the treatment of acne (acne vulgaris). Has antimicrobial activity against gram-positive bacteria that cause acne development. Due to the release of oxygen inhibits the development of the anaerobic microflora (Propionibacterium acnes) in acne, thereby decreasing the allocation of provoking disease fatty acids in the infected follicles. Benzoyl peroxide also has a keratolytic effect, contributing to skin exfoliation and removal of the horny layer around the comedones.
After a small amount of resorption from the skin surface is metabolized into benzoic acid and benzoate is excreted as urine.
Indications: acne vulgaris (acne vulgaris).

APPLICATION Benzoyl Peroxide Gel:

Before applying the 5 and 10% lotion or gel, benzoyl peroxide, the affected skin thoroughly washed and dried with a soft clean towel. Apply to affected skin and rub until completely absorbed. After using the wash your hands thoroughly. Early treatment may be an imaginary deterioration associated with increased skin peeling on the affected areas. Sensitive skin lotion is applied with care to avoid congestion and peeling. In the first week of treatment applied 1 time a day if the local reactions do not occur, benzoyl peroxide is used 2 times a day. Should not be used in the elderly. The average duration of treatment benzoyl peroxide is 8-10 weeks, you should not use it more than 3 months. In severe cases, topical application of benzoyl peroxide combined with other drugs to treat acne (antibiotics or oral retinoids).

CONTRAINDICATIONS Benzoyl Peroxide Gel:

Hypersensitivity to benzoyl peroxide.

SIDE EFFECTS Benzoyl Peroxide Gel:

burning and stinging sensation, excessive skin irritation at the site of application Valium.

PRECAUTIONS Benzoyl Peroxide Gel:

Avoid contact with eyes and mucous membranes. To prevent hypersensitivity reactions is recommended experimental application Valium on a small area of skin at the wrist. If within 48 hours in this place will be swelling, or itching with severe hyperemia, apply benzoyl peroxide should not be. With prolonged use may be redness or peeling. In severe reactions should reduce the amount of funds deposited and the frequency of its use.
Used with caution during pregnancy and lactation. Benzoyl peroxide stimulates mitosis of epidermal cells, leading to acanthosis and hyperkeratosis, the emergence of scaling and redness of the skin determines the period of alleged deterioration during the first weeks of treatment.
Individuals with fair skin and blond hair, and with sensitive skin should start treatment with 5% p-ra 1 per day.

INTERACTION :

Simultaneous with the appointment of Adapalene

OVERDOSE Benzoyl Peroxide Gel:

If overdose is noted excessive redness, dryness and peeling. The symptoms disappear with discontinuation of funds. It is recommended to wipe the skin with a gauze or a cotton swab dipped in vegetable oil. It is seldom necessary to apply a cream or ointment containing corticosteroids.

Adapalene

Pharmacological action Adapalene Gel:

Treatment for acne, anti-inflammatory effect. Binds to specific nuclear receptors, has komedonoliticheskoy activity normalizes the process of keratinization, and epidermal differentiation. Reduces the binding of follicular epithelial cells involved in the formation of mikrokomedonov. Inhibits chemotaxis and hemokineticheskie reaction polinuklearnyh cells in humans.

Uses Adapalene Gel:

Acne.

Contraindications Adapalene Gel:

Hypersensitivity, pregnancy, lactation. Dermatitis, seborrhea, eczema.

Side effects Adapalene Gel:

Hyperemia and desquamation at the site of application.

Dosage and administration Adapalene Gel:

Externally applied 1 time a day at bedtime to clean, dry skin, evenly, light touch, avoiding the eyes and lips. Clinical outcome occurs within 4-8 weeks of treatment, sustained improvements – after 3 months of treatment. In case of excessive application of the gel faster than the positive effect does not occur.

Cautions Adapalene Gel:

If skin irritation occurs discontinue use of the gel (either temporarily or altogether). Avoid exposure to the sun, in the event of prolonged sun exposure does not apply the gel the day before and the day of sun exposure and the following day. Do not use both cosmetic products with a drying or irritating effects (such as cologne or etanolsoderzhaschie means).

Interaction Adapalene Gel:

Simultaneous with the appointment of clindamycin or benzoyl peroxide.